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Diabetes Research Archives...

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Libre system reduces hypoglycemia  


Improving muscle health could enhance response to insulin  


Half of all Type 1 diabetes cases occur after age 30  


Novel SGLT inhibitor adds benefit to insulin in Type 1 diabetes  


New Glucose sensing Technology and hypoglycemia





c-peptide in Diabetes Management


Outcome Measures for Artificial Pancreas Clinical Trials


RRandomized trial of dual hormone artificial pancreas with dosing adjustments vs no adjustments & sensor augmented pump


Dogs Can sniff out diabetes


Artificial pancreas protocol deemed safe for young children with diabetes


Babies with cold or flu before 6 months are more likely to develop type 1 diabetes


Solving the genetic mystery of type 1 diabetes


Researchers produce insulin producing beta cells in a dish


Type 1 diabetes cell therapy enrolls first patients


NICE guidance on Sensor Augmented Insulin Pumps


Scientists create painless patch of insulin producing beta cells


The next step in preventing Type 1 diabetes


Is Psychological stress a factor to incorporate into a closed loop system?

Sanofi and JDRF work together on breakthrough insulin


Insulin producing mini-stomachs.  A game changer for diabetes?


Watson-Powered Diabetes App predicts Hypoglycemia


Artificial Pancreas to undergo long-term clinical studies.


Type 1 diabetes NOT linked to Vitamin D concentrations


Intranasal Glucagon





A smartphone could operate artificial pancreas
Depression often untreated in children with diabetes

Type 1 diabetes insulin vaccine undergoes 2nd trial


Negative feelings often precede insulin restriction in Type 1 diabetes


New staging approach for the development of Type 1 diabetes

At-Home Use of Artifical Beta Cells Beneficial in Type 1 diabetes
Diabetic Retinopathy screening can be delayed until age 15 or 5 years into diagnosis


NICE suggests GP set individual glucose targets


UK suggests tighter guidelines for people with diabetes


Insulin pump therapy reduces risk of CVD by half


DKA seen in 1 in 20 children with diabetes


Novo's chief medical officer talks innovations in diabetes drug developments


French partnership to develop an artificial pancreas


Association between number of comorbid medical conditions and

 depression among individuals with diabetes; race and ethnic variations


Medtronic seeking US participants for its closed loop study


Brown School Study looks at Twitter hashtags and diabetes


J&J starts project to prevent type 1 diabetes


Which artificial pancreas is best for children with type 1 diabetes?


Type 1 vaccine clears first hurdle


Camera study address children's perspective on living with Type 1 diabetes


Restoration of glucose counterregulation by Islet transplantation in long-standing Type 1 diabetes


CV Risk decreases with increased physical activity in people with Type 1 diabetes


4 year old makes history in world's 1st attempt at type 1 diabetes prevention


Treatment outcomes could improve in all groups of people with type 1 diabetes


Tight HbA1c reduces need for eye surgery


First hurdle taken on the way to insulin vaccine 


More children with Type 1 diabetes are experiencing life threatening complications

at time of diagnosis.


Young women with Type 1 diabetes more likely to have eating disorders


Intranasal glucagon for severe hypoglycemia


Transplant therapy helping patients with Type 1 diabetes


Effects of acute hypoglycemia on working memory and language

processing on adults with and without Type 1 diabetes


Promising vaccine strategy for Type 1 diabetes extended to humans


Combo happy Diamyd launches new diabetes vaccine trial in children

Tresiba approved in EU for use in children and adolescence with Type 1 diabetes


Lilly delays FDA submission on new basal insulin


Excessive deaths in women with type 1 diabetes


Painless Temporary Tattoo to check BG levels


New Insulin Glargine 300 effective in Type 1 diabetes


Health Canada grants ViaCyte clearance for diabetes clinical trial


Type 1 patients lives can be significantly improved by Artificial Pancreas


Low blood sugar levels may damage the heart


How does Type 1 diabetes impact the growth of a child's brain


Chronic High Blood Glucose Levels may impair brain development in children


Risk factors associated with increased mortality during early adulthood with type 1 diabetes


Low blood glucose may damage your heart


CGM in newly diagnosed Type 1 diabetes




August-October 2013


Biomarker Panel Could Provide Simpler Type-I Diabetes Detection


Diabetic Children test bionic pancreas at camp


Novo Nordisk launches Tresiba in India for Type 1 and Type 1 diabetes in India


Breakthrough method for diabetic transplants discovered


Up to half of all teenaged girls with Type 1 diabetes develop eating disorders

Family-based psychoeducation and care ambassador intervention to improve glycemic control in T1 youth

Goal disturbance and coping in children with T1D


Pediatric estimated average glucose in children with Type 1 diabetes


Factors associated with HbA1c one year after diagnosis.


Drug preserves beta cells in new cases of type 1 diabetes


Type 1 diabetes and living without a partner


Impact of T1D on Academic Performance


The incidence of severe hypoglycemia in pregnant women with T1D can be reduced with unchanged HbA1c levels

and pregnancy outcomes in a routine care setting.



July 2013


Childhood respiratory infection may increase risk of Type 1 diabetes


ADA: Intensive Tx Yields Long-Term Gain in Type 1 Diabetes


Medtronic, J&J Put Diabetics Nearer to Artificial Pancreas



May/June 2013


New Data on Islet Autoantibodies in Young Children Defines Early Type 1 Diabetes Development


Exercise and Teens with T1 diabetes


Goal disturbance and coping in children with T1D


Diabetes Attitudes, Wishes and Needs Study


Intense Physical Activity associated with lower A1c


Injectable nano particles maintain bg levels for up to 10 days


No connection between viral infection and T1 diabetes in children


Vaccine could delay onset


Predicting Kidney Disease in Diabetics


The LIFE Study


Low-income areas increase risks for diabetic children


Pitt, Mount Sinai Team Finds Novel Mechanism Regulating Replication Of Insulin-Producing

Beta Cells For Diabetes Treatment



April 2013


Low Morbidity and Mortality in Children with Diabetic Ketoacidosis Treated with Isotonic Fluids 


The impact of bg and A1c goals on children and adolescents with T1 diabetes


Comparison of the Effect of Insulin Glulisine to Insulin Aspart on Breakfast Postprandial

Blood Glucose Levels in Children with Type 1 DM on Multiple Daily Injections 


February/March 2013


Association between glucose variability as assessed by continuous glucose monitoring (CGM)

 and diabetic retinopathy in type 1 and type 2 diabetes


The risk of early cardiovascular disease in Lithuanian diabetic children and adolescents


Artificial Pancreas better alternative than pump


Comparing Glycemic control in children with type 1 diabetes on insulin pumps versus MDI


Comparison of annual variability in HbA1c and glycated albumin in patients with type 1 vs. type 2 diabetes mellitus 



January 2013


Searching for Genetic Clues to insulin production


What is the ideal BP targets for people with diabetes


Testing New Insulin


SANOFI : and T1D Exchange to Launch Worldwide Study to Investigate Factors for Optimal

Care for Young People with Diabetes


Early Life Socioeconomic Indicators and Risk of Type 1 Diabetes in Children and Young Adults


C8 MediSensors Gains CE Mark Approval for C8 MediSensors Optical Glucose Monitor(TM) System for People with Diabetes




October 2012


Research to determine how genes contribute to Type 1 diabetes


The use and efficacy of continuous glucose monitoring in type 1 diabetes treated with insulin pump therapy


Metabolic and Inflammatory Links to Depression in Youth With Diabetes


Diabetes Patients Face Higher Risk of Stroke and Heart Attack


Stop Diabetes with Insulin Tablets


Adults with Type 1 diabetes may be at risk for thinning bones


Parental Stress and Depression in T1D teens


Men with Type 1 Osteoporosis Risk



September 2012


A Population-Based Study of the Risk of Diabetic Retinopathy in Patients With Type 1 Diabetes and Celiac Disease 


Good news for diabetics, no more pinpricks


A pediatric tool box for creating centers of reference


A diabetes scorecard does not improve HbA1c, blood pressure, lipids, aspirin usage, exercise

and diabetes knowledge over 9 months: a randomized controlled trial 


Seeking a cure for Type 1 Diabetes--Identifying precursors to insulin producing cells


Pinprick testing in Diabetes could be a thing of the past


Mortality Among Low-Income African Americans and Whites With Diabetes



August 2012

Type 1 diabetes could be treated with a patch


New Blood sugar testing techniques better than old ones.


Diastolic Function is Reduced in Adolescents With Type 1 Diabetes in Response to Exercise 


July 2012


Trends in maternal BMI, glycaemic control and perinatal outcome among type 1 diabetic pregnant women in 1989-2008 


Tattoos Replacing Medical Alert Bracelets


Liraglutide with Insulin Improves Poorly Controlled Type 1 Diabetes


Type 1 Diabetes on the Rise among Youth


More Progress Made on Artificial Pancreas for Diabetes Patients


June 2012


SYMLIN(R) Use Helped Patients with Type 2 or Type 1 Diabetes Achieve More Time in Normal Glucose Range


JDRF-HCT merge with Medtronic to create artificial pancreas system for diabetes


Eating Disorder Poses Problem in Some Diabetics.


Study shows diabetic complications occur earlier in women with eating disorders


Tight Glucose Control No Help to Kidneys


Type 1 diabetes and celiac disease in adults: glycemic control and diabetic complications


May 2012


Studies find Mental Health Link to Diabetes


First Automated Insulin Dosage Titration System Demonstrates Positive Results in Clinical Study, Says Hygieia, Inc.


Procedure offers new hope in Type 1 diabetes


Novo Nordisk Escalates Research Efforts for Curing Type 1 Diabetes


Growth differences between North American and European children at risk for type 1 diabetes

Long-Term (5 Years) Efficacy and Safety of Pancreas Transplantation Alone in Type 1 Diabetic Patients

Parent–adolescent dyads: association of parental autonomy support and
parent–adolescent shared diabetes care responsibility

April 2012

Insulin analogues and severe hypoglycaemia in type 1 diabetes


Whole-Blood Tissue Factor Procoagulant Activity Is Elevated in Type 1 Diabetes


and Effects of Hyperglycemia and Hyperinsulinemia


The importance of HbA1c and glucose variability in patients with type 1 and type 2 diabetes:
outcome of continuous glucose monitoring (CGM)

Study provides important clue in Type 1 diabetes


Stress in the Beta Cells may provoke the development of Type 1 diabetes


Artificial Pancreas approved for US out patient trials


February/March 2012

Islet Function Improved with Enhanced Oxygen and GHRH Agonist in Bioartificial Pancreas

Insulin production may persist decades after onset of type 1 diabetes

Twins key to juvenile diabetes study at VU

Integrating an Automated Diabetes Management System Into the Family Management of Children With Type 1 Diabetes Results from a 12-month randomized controlled technology trial

Hyperglycemia and Adverse Pregnancy Outcome (HAPO) Study Associations of maternal A1C and glucose with pregnancy outcomes

Continuous Subcutaneous Insulin Infusion of Insulin Lispro in Children and Adolescents with Type 1 Diabetes

Age-related islet autoantibody incidence in offspring of patients with type 1 diabetes

Type 1 Diabetes Treatment Disappoints in Trial. Vaccine-based approach didn't affect insulin needs or other markers

Calgary company may have treatment that can prevent, reverse diabetes

Retinal Vascular Geometry Predicts Incident Renal Dysfunction in Young People With Type 1 Diabetes

Stems cells may reverse Type 1 diabetes


January 2012

Type 1 Diabetes Prevention better than a cure?

Themes elicited during motivational interviewing to improve glycaemic control in adults with Type 1 diabetes mellitus

Effect of exercise intensity on albuminuria in adolescents with Type 1 diabetes mellitus

FDA guides novel diabetes device manufacturers towards easier approval


December 2011

Tighter Glucose Control Linked with decreased prevalence of Retinopathy in adolescents with Type 1 Diabetes

A Propensity-Matched Study of the Association of Diabetes Mellitus With Incident Heart Failure and Mortality Among Community-Dwelling Older Adults

Smoking is associated with impaired long-term glucose metabolism in patients with type 1 diabetes mellitus

Increased Risk of Urinary Tract Calculi Among Patients with Diabetes Mellitus—A Population-based Cohort Study

Kidney disease risk may be reduced by intensive type 1 diabetes therapy


November 2011

Andromeda's Type 1 Diabetes Drug DiaPep277 Meets Primary Endpoint In Phase 3

Association of Epilepsy and Type 1 Diabetes Mellitus in Children and Adolescents: Is There an Increased Risk for Diabetic Ketoacidosis?

In Type 1 Diabetes, Intensive Therapy Halves Kidney Disease

Testing Blood Sugar In Diabetes Via Tear Drops

Periodontitis and diabetes:  A two way relationship

Intensive diabetes care cuts kidney complications

Fountain Goes Blue to Eradicate Diabetes

Medtronic Receives IDE Approval to Conduct ASPIRE In-Home Study of First Insulin Pump with Low Glucose Suspend for US Market A Critical Step Toward the Development of an Artificial Pancreas, Low Glucose Suspend Aims to Reduce Hypoglycemia

Last Decade Saw Marked Drop in Diabetes-Linked Retinopathy

New Study Aims to Help Youths Better Manage Type 1 Diabetes

Halozyme Ultrafast Insulin Trials in diabetics yield positive data


October 2011

Joint Venture Breathes New Life into Type 1 Diabetes Treatment, as Reported by DiabeticLive.com

Halozyme Announces Positive Results From Phase 2 Ultrafast Insulin Trials in Patients with Type 1 and Type 2 Diabetes

Effect of sitagliptin on glucose control in adult patients with Type 1 diabetes: a pilot, double-blind, randomized, crossover trial

Brain Activation During Working Memory Is Altered in Type 1 Diabetes During Hypoglycemia

Effect of sitagliptin on glucose control in adult patients with Type 1 diabetes: a pilot, double-blind, randomized, crossover trial

Brain volume affected by glycaemia in diabetics, according to study.  For parents who are fighting to get schools to understand the real impact of highs and lows on their children, this study is for you.

New guidelines suggest continuous glucose monitoring may be beneficial to type 1 diabetics

Large Meta-Analysis Finds New Genes For Type 1 Diabetes

Healthy first degree relatives of patients with type 1 diabetes exhibit significant differences in basal gene expression pattern of immunocompetent cells compared to controls: expression pattern as predeterminant of autoimmune diabetes

Reducing Rates of Severe Hypoglycemia in a Population-Based Cohort of Children and Adolescents With Type 1 Diabetes Over the Decade 2000–2009

Associations Between Media Consumption Habits, Physical Activity, Socioeconomic Status, and Glycemic Control in Children, Adolescents, and Young Adults With Type 1 Diabetes

EASD: Meta-Analysis Confirms Value of CGM in Type 1 Diabetes

September 2011

Type 1 diabetes disease characteristics differ based on age at diagnosis

Implications of Nocturnal Hypertension in Children and Adolescents With Type 1 Diabetes

Fetal tissue plays pivotal role in formation of insulin-producing cells

Reproductive Cells May Some Day Treat Women with Diabetes

Changes in Altitude Cause Unintended Insulin Delivery From Insulin Pumps Mechanisms and implications

Diabetes screening with hemoglobin A1c prior to a change in guideline recommendations: prevalence and patient characteristics

Does Blood Glucose Monitoring Increase Prior to Clinic Visits in Children With Type 1 Diabetes?

Adult Stem Cell Memories could aid in Type 1 diabetes treatment

Glycaemic control and incidence of heart failure in 20 985 patients with type 1 diabetes: an observational study

Pin Pricks for Blood Sugar Testing Could Be History With New Sensor for Children


July 2011

Young People With Type 1 Diabetes at Risk for Heart Disease, Research Shows

Study Suggests Drug Significantly Improves Glycemic Control in Type 1 Diabetics on Insulin

First human evidence that nasal vaccine could prevent type 1 diabetes

Embryonic Stem Cell Research Focuses on Diabetes

A Bridge to Insulin Pump Therapy: Bid Regimen with NPH and Detemir Insulin During Initial Treatment of Youth with Type 1 Diabetes (T1D) 

J&J dumps $625M diabetes drug pact with Diamyd

Combination of Two Type 1 Diabetes Medication Testing to Help Limit the Number of Injection

JDRF, Amylin Investigate Type 1 Diabetes Treatment

Team Type 1 Diabetes Sports Research Institute to Launch First of Its Kind Clinical Study at Amgen Tour of California May 15-22

Diamyd’s Type 1 Diabetes Candidate Fails in European Phase III Study


June 2011

Embryonic Stem Cell Research Focuses on Diabetes

A Bridge to Insulin Pump Therapy: Bid Regimen with NPH and Detemir Insulin During Initial Treatment of Youth with Type 1 Diabetes (T1D) 

J&J dumps $625M diabetes drug pact with Diamyd

Combination of Two Type 1 Diabetes Medication Testing to Help Limit the Number of Injection

JDRF, Amylin Investigate Type 1 Diabetes Treatment

Team Type 1 Diabetes Sports Research Institute to Launch First of Its Kind Clinical Study at Amgen Tour of California May 15-22

Diamyd’s Type 1 Diabetes Candidate Fails in European Phase III Study


May 2011

Structured Exercise Training Associated With Improved Glycemic Control for Patients With Diabetes

Artificial Pancreas shown effective in overnight diabetes management.

The utility of hemoglobin A1c at diagnosis for prediction of future glycemic control in children with type 1 diabetes

Key elements for successful intensive insulin pump therapy in individuals with type 1 diabetes

Artificial pancreas promise for common diabetes complication

Lower HbA1c after 1 year, in children with type 1 diabetes treated with insulin glargine vs. NPH insulin from diagnosis: a retrospective study


April 2011

Lower HbA1c after 1 year, in children with type 1 diabetes treated with insulin glargine vs. NPH insulin from diagnosis: a retrospective study

Prevalence of Nocturnal Hypoglycemia in Pediatric Type 1 Diabetes: A Pilot Study Using Continuous Glucose Monitoring

Levemir Better for Treating Young Children with Type 1 Diabetes Than Human Basal Insulin

Association of DASH Diet With Cardiovascular Risk Factors in Youth With Diabetes Mellitus

New Device Holds Promise Of Making Blood Glucose Testing Easier For Patients With Diabetes

Real-time continuous glucose monitoring system for treatment of diabetes: a systematic review

March 2011

Effects of Carbohydrate Counting on Glucose Control and Quality of Life Over 24 Weeks in Adult Patients With Type 1 Diabetes on Continuous Subcutaneous Insulin Infusion

Diabetics face heightened risk of premature death

TrialNet Study Seeks Answers to Type 1 Diabetes Questions

Study:  50 year old with diabetes dies 6 years earlier

Diabetes can take six years off your life by increasing risk of cardiovascular disease and cancer, study says

Diabetic Wound Healing Improved By Human Umbilical Cord Blood Cells

Risk for ESRD in Type 1 Diabetes Remains High Despite Renoprotection

A1C Variability as an Independent Risk Factor for Microalbuminuria in Young People With Type 1 Diabetes

Need for xenotransplantation in the treatment of type 1 diabetes

Frequency of symptomatic and asymptomatic hypoglycaemia in Type 1 diabetes: effect of impaired awareness of hypoglycaemia

February 2011

Intensive Diabetes Treatment may slow atherosclerosis

Type 1 Diabetes Patients Need New Kidney Therapies: Study

Self-Monitoring of Blood Glucose: The Use of the First or the Second Drop of Blood

Characterizing sudden death and dead-in-bed syndrome in Type 1 diabetes: analysis from two childhood-onset Type 1 diabetes registries

Early signs of heart disease in preadolescent children with type 1 diabetes

Use of Continuous Glucose Monitoring in Subjects With Type 1 Diabetes on Multiple Daily Injections Versus Continuous Subcutaneous Insulin Infusion Therapy A prospective 6-month study

The outcome of brittle type 1 diabetes—a 20 year study

Cold like virus 'could trigger Type 1 diabetes'

High blood sugar rates linked to stroke severity

Artificial Pancreas shows promise in pregnancy

UT Southwestern researchers uncover potential 'cure' for type 1 diabetes

Insulin Degludec in Type 1 Diabetes A randomized controlled trial of a new-generation ultra-long-acting insulin compared with insulin glargine

January 2011

Link between depression and type 1 diabetes reported

FDA issues CRL to MannKind Afrezza NDA

Pre-eclampsia Risk for Women with Type 1 Diabetes Unaffected by Vitamin C & E Supplements

Diabetes Defeated by a microchip? Silicon pancreas hits trail

Type 2 diabetes drug shows promise for Type 1

Energy and Nutrient Intakes and Adherence to Dietary Guidelines among Finnish adults with Type 1 diabetes

Renal Glucose Reabsorption Inhibitors to treat diabetes

Diabetes Control in Pregnancy Key to Children's Health

HbA1c levels in schoolchildren with type 1 diabetes are seasonally variable and dependent on weather conditions

New Insulin Injection offer protection for diabetes patients.

Association between childhood obesity and subsequent Type 1 diabetes: a systematic review and meta-analysis

December 2010

DiaMedica Announces Positive Final Results in Type 1 Diabetes Study

JDRF and Amylin Pharmaceuticals Partner to Investigate Metreleptin As Potential Therapy to Improve Glucose Control

Major Milestone Reached for People with Diabetic Eye Disease

Are blood ketones a better predictor of than urine ketones of acid based balance in DKA?

Using Sperm-Producing Cells to Treat Type 1 Diabetes

Study: Cure for Males with Type 1 diabetes closer

November 2010

FDA Rejects BioDel's Diabetes Drug: BioTech's Latest Mishap

Insulin Pump Management Consensus Statement Released by AACE

Continuous Glucose Monitoring Statement Released by AACE

October 2010

How leptin therapy improves type 1 diabetes

Parental Involvement and Adolescents' Diabetes Management: The

Mediating Role of Self-Efficacy and Externalizing and Internalizing Behaviors.

The prevalence and risk factors for coeliac disease among children and adolescents with type 1 diabetes mellitus

T Cell Discovery Brings Hope for Type 1 Diabetes

Continuous subcutaneous insulin infusion in Type 1 diabetes: patient experiences of 'living with a machine'

Evolution and predictors of morphological and functional arterial changes in the course of type 1 diabetes mellitus

$5 Million Boost For Type 1 Diabetes Research At UC San Diego

New insulin could cut need for daily injections

Need for early recognition of type 1 diabetes, says expert

September 2010

Artificial pancreas offers hope

Survey Data Reveals Shocking 'Insulin Pump Postcode Lottery'

Patients’ evaluation of nocturnal hypoglycaemia with GlucoDay continuous glucose monitoring in paediatric patients

Dead in bed: a tragic complication of type 1 diabetes mellitus

August 2010

Groundbreaking wireless sensor will monitor diabetics' glucose levels from the INSIDE

"Dead in bed": a tragic complication of type 1 diabetes mellitus.

Confirmation of hypoglycemia in the "dead-in-bed" syndrome, as captured by a retrospective continuous glucose monitoring system.

July 2010

Regrowing body parts closer to reality

Transplanted Beta Cells Learning to Protect Themselves
ADA: Sensor-Augmented Insulin Pump Therapy Wins Over Multiple Daily Injections for Type 1's

ADA: Continuous Glucose Monitoring Only Successful with Knowledge and Support

Diabetic potential to create own insulin

Aspirin Recommendations Changed For Many Younger Diabetic Patients

A Review of Inhaled Technosphere Insulin

June 2010

Maternal and neonatal risk factors for childhood type 1 diabetes: a matched case-control study

Enhanced Accuracy of Continuous Glucose Monitoring by Online Extended Kalman Filtering

The importance of glycemic control: how low should we go with HbA1c? Start early, go safe, go low

May 2010

Bone status in adolescents with type 1 diabetes
Nocturnal hypoglycemia frequent, prolonged in those with type 1 diabetes

Occurrence of microalbuminuria in young people with Type 1 diabetes: importance of age and diabetes duration

April 2010

Parents' Fear Of Hypoglycaemia Impacts On Children's Diabetes Management

'Pig sushi' diabetes trial brings xenotransplant hope

Plasma glucose and hypoglycaemia following exercise in people with Type 1 diabetes: a comparison of three basal insulins

Parental Involvement Buffers Associations Between Pump Duration and Metabolic Control among Adolescents with Type 1 Diabetes

Leptin therapy shows promise for diabetes

March 2010

Overweight Is Highly Prevalent In Children with Type 1 Diabetes And Associates with Cardiometabolic Risk.

Meter Accuracy

Aggressive Treatments Don't Help Diabetes Patients

Islet amyloid deposition limits the viability of human islet grafts but not porcine islet grafts

UT Southwestern researcher ready to test new diabetes treatment in humans

Is bedtime supper necessary for older children with diabetes using glargine insulin in multiple daily injection regimens?

MD-Logic Artificial Pancreas System: A Pilot Study in Adults with Type 1 Diabetes Mellitus

February 2010

Artificial Pancreas System Helps Control Nighttime Hypoglycemia

Manual closed-loop insulin delivery in children and adolescents with type 1 diabetes: a phase 2 randomised crossover trial

Approval of Diamyd's Diabetes Vaccine Set for 2011

Ethnic Differences in Incidence of Type 1 Diabetes among Second-Generation Immigrants and Adoptees from Abroad

January 2010

Missed Insulin Boluses for Snacks in Youth with Type 1 Diabetes

Up to 10% of Children with Type 1 Diabetes have Celiac Disease

Progression to diabetes in relatives of type 1 diabetic patients: mechanisms and mode of onset.

JDRF Announces Diabetes Research Program with Johnson & Johnson

Diamyd Medical gets OK from FDA to test diabetes vaccine on small children

Association Of Tight Glycemic Control With Road Crashes In Diabetic Patients

December 2009

Sudden death in type 1 diabetes: The mystery of the ‘dead in bed’ syndrome

Variable A1C Linked to Renal Disease in Type 1 Diabetes

Cardiovascular Risk in Youth With Type 1 Diabetes Linked Primarily to Insulin Resistance

Transition to Adult Care for Youths With Diabetes Mellitus: Findings From a Universal Health Care System

The effect of biopsy-positive silent coeliac disease and treatment with a gluten-free diet on growth and glycaemic control in children with Type 1 diabetes

Psychological symptoms and insulin sensitivity in adolescents

Age at onset of Type 1 Diabetes in Parents and Recurrence risk in offspring

October/November 2009

A Pilot Trial of Pramlintide Home Usage in Adolescents With Type 1 Diabetes

Closed-Loop Insulin Delivery Using a Subcutaneous Glucose Sensor and Intra-Peritoneal Insulin Delivery: A Feasibility Study Testing a New Model for the Artificial Pancreas.

Brief Report: Parent's Health Literacy among High-Risk Adolescents with Insulin Dependent Diabetes

Pancreas transplantation alone in children: a case report.

September 2009

Accuracy and Reliability of Continuous Glucose Monitoring in Individuals with Type 1 Diabetes During Recreational Diving

Retinal Vascular Fractal Dimension and Risk of Early Diabetic Retinopathy: A Prospective Study of Children and Adolescents with Type 1 Diabetes

Association of type 1 diabetes with month of birth among US youth: The SEARCH for Diabetes in Youth Study

August 2009

Discovery Of A Gene That May Play A Role In Type 1 Diabetes

Chicago Diabetes Project

Predictors of Insulin Regimens and Impact on Outcomes in Youth with Type 1 Diabetes: The SEARCH for Diabetes in Youth Study

The effectiveness of glucose, sucrose, and fructose in treating hypoglycemia in children with type 1 diabetes

Low dose (0.05 units/kg/h) is comparable with standard dose (0.1 units/kg/h) intravenous insulin infusion for the initial treatment of diabetic ketoacidosis in children with type 1 diabetes-an observational study.

Continuous glucose monitoring in youth with type 1 diabetes.

June and July 2009

Inpatient care of patients with type 1 diabetes mellitus by duration of diabetes and sex: A nationwide population-based longitudinal study

Reducing glycaemic variability in type 1 diabetes self-management with a continuous glucose monitoring system based on wired enzyme technology

Exubera Inhaled Insulin in Patients with Type 1 and Type 2 Diabetes: The First 12 Months

May 2009

The link between type 1 diabetes and celiac disease

Comparison of a Multiple Daily Insulin Injection Regime (Basal Once-Daily Glargine plus Mealtime Lispro) and CSII (Lispro) in Type 1 Diabetes: a Randomized Open Parallel Multicenter Study

Institution of Basal-Bolus Therapy at Diagnosis for Children With Type 1 Diabetes Mellitus

Cognitive Function is Disrupted by Both Hypo- and Hyperglycemia in School-Aged Children with type 1 diabetes: A Field Study

Electronic Device For Quick And Painless Glucose Test To Aid Diabetics Designed By Biomedical Engineers At University Of Calgary

Patients With Type 1 Diabetes May Get Cure From Stem Cells

April 2009

Prevalence and Correlates of Depression in Individuals With and Without Type 1 Diabetes

Antibiotic Use and Type 1 Diabetes in Childhood

Next-Generation Sequencing Uncovers Genetic Variation Linking Type 1 Diabetes With Enterovirus Infection

March 2009

New Study Of Human Pancreases Links Virus To Cause Of Type 1 Diabetes - May Lead To A Vaccine

Low-glycaemic index sweetener-based beverages reduce 24-h glucose profiles in healthy adults

Effect of popular takeaway foods on blood glucose levels in type 1 diabetes mellitus patients on intensive insulin therapy.

January/February 2009

Explaining the Adjustment of Adolescents with Type 1 Diabetes: The Role of Diabetes-Specific and Psychosocial Factors

Missed bolus doses: devastating for metabolic control in CSII-treated adolescents with type 1 diabetes

Changing basal insulin from NPH to detemir or glargine in patients with type 1 diabetes and a history of severe hypoglycemia

Improved glycaemic control by switching from insulin NPH to insulin glargine: a retrospective observational study

Encapsulated porcine islet transplantation: an evolving therapy for the treatment of type I diabetes.

Current status of islet cell transplantation.

A multi-year analysis of islet transplantation compared with intensive medical therapy on progression of complications in type 1 diabetes.

December 2008

Hypoglycemia with intensive insulin therapy. A systematic review and meta-analyses of randomized trials of continuous subcutaneous insulin infusion versus multiple daily injections

Breakthrough In Understanding Development Of Type 1 Diabetes

No benefit for nasal insulin in preventing, delaying type 1 diabetes

New Study Finds Changes In Position Of Conventional Insulin Pumps Can Cause Fluctuations In Insulin Delivery Rates

November 2008

Psychological Therapy to Improve Control of Type 1 Diabetes

Diabetes Type 1 Vaccine - Diamyd(R) Phase III Study Approved By Six European Countries

Study Looks At Impact Of Insulin Pump

Cardiac arrhythmia and nocturnal hypoglycaemia in type 1 diabetes—the ‘dead in bed’ syndrome revisited

Type 1 Diabetes May Be Based on Gene-Expression Signatures rather than Specific Variants

Relationship between beta-cell mass and diabetes onset.

Lessons learned from studies of the natural history of diabetic nephropathy in young type 1 diabetic patients.


October 2008

GAD Treatment and Insulin Secretion in Recent-Onset Type 1 Diabetes

Type 1 Diabetes May Result From Good Genes Behaving Badly

New Zealand to trial pig cells as treatment for type 1 diabetes

September 2008

'Friendly' Bacteria Protect Against Type 1 Diabetes, Yale Researchers Find

Pre-meal blood sugar values most informative: study

New Study Demonstrates Glucose Device Rapidly Alleviates Major Symptom Of Type 1 Diabetes In Children

A Study Assessing an Injection Port for Administration of Insulin 

Devise to Control Blood Sugar Benefits Type 1 Diabetes Patients

Young Women With Type 1 Diabetes Have Lower Bone Mineral Density That Persists Over Time 

August 2008

A novel insulin formulation with a more rapid onset of action

Insulin Glargine Versus Intermediate-Acting Insulin as the Basal Component of Multiple Daily Injection Regimens for Adolescents with Type 1 Diabetes Mellitus.

July 2008

Effects of inhaled human insulin on airway lining fluid composition in adults with diabetes

Children developing type 1 diabetes before 6 years of age have increased linear growth independent of HLA genotypes

LCT Informed Of Progress For Decision On Diabetes Clinical Trial In New Zealand

Effects of insulin pump vs. injection treatment on quality of life and impact of disease in children with type 1 diabetes mellitus in a randomized, prospective comparison 

Unique Drug Combination May Hold The Key To Reversing Type I Diabetes

June 2008

Unique drug combination may hold the key to reversing Type I diabetes

Vitamin D May Cut Risk Of Type 1 Diabetes. Babies, Children Should Be Given Vitamin D Supplements, Researchers Say 

Insulin Glargine Maintains Equivalent Glycemic Control and Better Lipometabolic Control than NPH Insulin in Type 1 Diabetes Patients Who Missed a Meal

Type 1 Diabetes In Finnish Children Skyrockets

Islet Cell Transplants Aid Type 1 Diabetics.  Study participants lived insulin-free for at least a year or two

May 2008

Evidence Discovered For Suspected Cause Of Type 1 Diabetes

Acute Complications and Drug Misuse Are Important Causes of Death for Children and Young Adults With Type 1 Diabetes

Blood pressure in diabetic kids needs watching

Discovery Leads to Earlier Diagnosis of Type 1 Diabetes.  Researchers identify molecular signature in human type 1 diabetes 

Insulin intervention in slowly progressive insulin-dependent (type 1) diabetes mellitus

April 2008

Daily insulin requirement of children and adolescents with type 1 diabetes: effect of age, gender, body mass index and mode of therapy. 

Hyperglycaemia as a determinant of cognitive decline in patients with type 1 diabetes.

The impact of an assisted diabetes care programme on a private practice

Are family factors universally related to metabolic outcomes in adolescents with Type 1 diabetes?

Prevalence of impaired awareness of hypoglycaemia in adults with Type 1 diabetes

Long-term efficacy and safety of insulin detemir compared to Neutral Protamine Hagedorn insulin in patients with Type 1 diabetes using a treat-to-target basal–bolus regimen with insulin aspart at meals: a 2-year, randomized, controlled trial

Measurement of Insulin Sensitivity in Children.  Comparison between the euglycemic-hyperinsulinemic clamp and surrogate measures

Time series analysis of ultraviolet B radiation and type 1 diabetes in Newfoundland

Improved glycemic control and lower frequency of severe hypoglycemia with insulin detemir; long-term experience in 105 children and adolescents with type 1 diabetes

Very high and increasing incidence of type 1 diabetes mellitus in Newfoundland and Labrador, Canada

March 2008

Phosphagenics Initiates Its Phase 2 Clinical Trial In Type 1 Diabetes

Perinatal risk factors for early childhood onset type 1 diabetes in Austria – a population-based study (1989–2005)

Use of the DirecNet Applied Treatment Algorithm (DATA) for diabetes management with a real-time continuous glucose monitor (the FreeStyle Navigator) 

Teenagers with type 1 diabetes—a phenomenological study of the transition towards autonomy in self-management

Age-specific Characteristics of the Basal Insulin-rate for Pediatric Patients on CSII

Sensor-augmented pump therapy in type 1 diabetes.

Human Insulin Analog–Induced Lipoatrophy

Relationship of A1C to Glucose Concentrations in Children With Type 1 Diabetes

Quality of life and treatment satisfaction in adults with Type 1 diabetes: a comparison between continuous subcutaneous insulin infusion and multiple daily injections

Hypoglycemia in Type 1 Diabetes. A still unresolved problem in the era of insulin analogs and pump therapy

Long-Acting Insulin Analogs Versus Insulin Pump Therapy for the Treatment of Type 1 and Type 2 Diabetes

February 2008

Quality of life and treatment satisfaction in adults with Type 1 diabetes: a comparison between continuous subcutaneous insulin infusion and multiple daily injections
Study suggests quality of life gains deriving from greater lifestyle flexibility, less fear of hypoglycaemia, and higher treatment satisfaction, when CSII is compared with either glargine-based or NPH-based MDI regimens.

Fully Automated Closed-Loop Insulin Delivery vs. Semi-Automated Hybrid Control in Pediatric Patients with Type 1 Diabetes using an Artificial Pancreas

Basal insulin switch from NPH to glargine in children and adolescents with type 1 diabetes

Very high and increasing incidence of type 1 diabetes mellitus in Newfoundland and Labrador, Canada.

Does the secular increase in body mass in children contribute to the increasing incidence of type 1 diabetes?

Transplanted Pig Cell Islets: A Solution For Diabetes Sufferers? USA

High prevalence of cardiovascular risk factors in children and adolescents with type 1 diabetes: a population-based study.

Comparison of continuous subcutaneous insulin infusion (CSII) and multiple daily injections (MDI) in paediatric Type 1 diabetes: a multicentre matched-pair cohort analysis over 3 years.

January 2008

Detection of a Meal Using Continuous Glucose Monitoring (CGM): Implications for an Artificial β-cell 

Pig Islet Cells: The Solution For Diabetes?

The role of partner relationships in the young person's adherence to the diabetes self-care regime.

International Initiative To Study Viruses Implicated In Type I Diabetes Launched In London

A genome-wide scan for type 1 diabetes susceptibility genes in nuclear families with multiple affected siblings in Finland

December 2007

Effect of apple cider vinegar on delayed gastric emptying in patients with type 1 diabetes mellitus: a pilot study.

Hospital admission patterns subsequent to diagnosis of type 1 diabetes in children : a systematic review

Delayed recovery of cognitive function following hypoglycemia in adults with type 1 diabetes: effect of impaired awareness of hypoglycemia

Mean blood glucose compared with HbA(1c) in the prediction of cardiovascular disease in patients with type 1 diabetes

Insulin glargine improves fasting blood glucose levels in prepubertal children with unsatisfactorily controlled type 1 diabetes 

Seasonality of month of birth differs between type 1 diabetes patients with pronounced beta-cell autoimmunity and individuals with lesser or no beta-cell autoimmunity. 

Defining the role of insulin detemir in Basal insulin therapy. 

November 2007

A morning dose of insulin glargine prevents nocturnal ketosis after postprandial interruption of continuous subcutaneous insulin infusion with insulin lispro. 

Continuous subcutaneous insulin infusion benefits quality of life in preschool-age children with type 1 diabetes mellitus 

October 2007

Statins May Benefit Kids With Recalcitrant Lipids New recommendations point to drug therapy when dietary change fails 

The Effect of Cinnamon on Glucose Control and Lipid Parameters
br/> Diabetic Breath Analysis Offers Potential For Noninvasive Blood Sugar Monitoring

New sources of pancreatic beta cells

The International Diabetes Federation (IDF) Recommends Tighter Control Of Blood Glucose Levels After Meals In People With Diabetes

New Data Supports Long-Term Efficacy And Safety In Patients Who Took Exubera For Eight Years

August and September 2007

Predictors of cognitive impairment in type 1 diabetes.

Alba Therapeutics Announces IND For Beta Cell Preservation In Type 1 Diabetes Using AT-1001

Inhaled Insulin Shows Short-term Safety

New studies assuage some concerns, but long-term effects still uncertain

The association of early atherosclerosis and retinopathy in adolescents with type 1 diabetes: preliminary report.

Hyperglycemia and Externalizing Behavior in Children With Type 1 Diabetes

Continuing Stability of Center Differences in Pediatric Diabetes Care: Do Advances in Diabetes Treatment Improve Outcome?

The influence of long-term therapy with the insulin pump (CSII) in patients with type 1 diabetes mellitus on metabolic compensation and on the incidence of hypoglycaemia. Comparison with intensified conventional insulin therapy (MDI).

Researchers Focus On Inflammation In War Against Type 1 Diabetes

July 2007

Insulin Capsules Have Potential To Prevent Diabetes Before Symptoms Appear And Treat The Disease In Its Later Stages

Refining basal insulin therapy: what have we learned in the age of analogues?

Influence of glycemic variables on hemoglobin a1c.

New Type 1 Diabetes Gene Found In Children

Comparison between basal insulin glargine and NPH insulin in patients with diabetes type 1 on conventional intensive insulin therapy

May/June 2007

Pancreatic islet transplantation, what has been achieved since Edmonton break-through

Novel Delivery Method Of Insulin Gene To Combat Juvenile Diabetes Developed

Oral Insulin To Prevent Type 1 Diabetes Tested By Study

Three-yr follow-up of a type 1 diabetes mellitus patient with an islet xenotransplant

Diabetes Linked To Male Infertility

Queen's Research Shows Diabetes Damages Sperm And May Affect Fertility

Significant Strides Being Made Against Diabetic Retinopathy

Disposable Insulin Nanopump from Debiotech and STMicroelectronics Marks Major Breakthrough in Diabetes Treatment

April 2007

The Role of Parental Monitoring in Adolescent Health Outcomes: Impact on Regimen Adherence in Youth with Type 1 Diabetes.

Seeking the Factors Predisposing to Local Skin Inflammatory State

Development in Children with Type 1 Diabetes (T1DM) Treated with Continuous Subcutaneous Insulin Infusion (CSII).

Pancreatic Cells Show Variable Plasticity

Type I diabetics live without insulin in stem cell experiment

Stem Cells -- a Possible Cure for Diabetes

Shorter remission period in young versus older children with diabetes mellitus type 1.

Novel Peptide Could Boost Availability And Success Of Islet Cell Transplant For Type-1 Diabetes

Diamyd Medical Announces Phase III Clinical Trials Plan For Diamyd(R) In Type 1 Diabetes

Protein Makes It Possible For High Blood Glucose To Enter Embryonic Cells

Successful Islet Cell Transplant Without Immunosuppressive Therapy In Mice With Type 1 Diabetes

March 2007

Defective Awakening Response to Nocturnal Hypoglycemia in Patients with Type 1 Diabetes Mellitus

Awakening from Sleep and Hypoglycemia in Type 1 Diabetes Mellitus

The relationship between ACE genotype and risk of severe hypoglycaemia in a large population-based cohort of children and adolescents with type 1 diabetes.

Classification of Distinct Baseline Insulin Infusion Patterns in Children and Adolescents With Type 1 Diabetes on Continuous Subcutaneous Insulin Infusion Therapy

Perceptions of Psychosocial Factors and the Insulin Pump

School performance in children with type 1 diabetes-a population-based register study

Chronic Care Model Associated with Improved Diabetic Control

February 2007

Study Tests Oral Insulin to Prevent Type 1 Diabetes

Foxp3 occupancy and regulation of key target genes during T-cell stimulation

Mom's Stem Cells Might Treat Child's Diabetes

January 2007

Phase II/III Clinical Trial Of Anti-CD3 Monoclonal Antibody For Children And Adults With Recent-Onset Type 1 Diabetes

Antibody Therapy Prevents Type 1 Diabetes In Mice

December 2006

Immune Responses Spread From One Protein To Another In Type 1 Diabetes

The effects of acute hypoglycaemia on memory acquisition and recall and prospective memory in type 1 diabetes.

Research Yields New Insights Into The Cause Of Diabetes

Treatment of new-onset type 1 diabetes with peptide DiaPep277(R) is safe and associated with preserved beta-cell function: extension of a randomized, double-blind, phase II trial.

The prevalence of depression and anxiety in adults with Type 1 diabetes

New Data From NIH Lab Confirms Protocol To Reverse Type 1 Diabetes In Mice

October 2006

MacroGenics Receives Orphan Drug Designation From FDA For Monoclonal Antibody To Treat Type 1 Diabetes

Researchers Eye Artificial Pancreas

Pancreatic Islet Transplantation
An interesting article explaining islet transplant therapy.

Diabetics get transplanted cells and eliminate the need for insulin shots

Edmonton Protocol Clinical Trial Findings Show Promise For Certain Patients With Severe Type 1 Diabetes

Important news for those diagnosed with neonatal type 1 diabetes...Targeted Therapy Turns Life Around For Child With Neonatal Diabetes

September 2006

Tight Control of Type 1 Diabetes: Recommendations for Patients

Researchers Uncover Gene That Raises Risk for Type 1 Diabetes

Microencapsulation of living cells to treat diabetes? Austrianova validates commercial potential of its proprietary encapsulation technology.

Therapy Insight: the impact of type 1 diabetes on brain development and function.

Summer 2006

Managing insulin therapy during exercise in type 1 diabetes mellitus.

Adult Stem Cell Research Breakthrough Produces Insulin for Diabetics

Researchers Find Glycemic Index Effective In Composite Meals, University Of Toronto

June 2006

Lilly, Alkermes: AIR insulin shown effective

Drug in development as treatment for Type I, Type II diabetes

Physical Activity Linked To Improved Glucose Control In Children With Type 1 Diabetes

May 2006

New study reveals signaling pathways required for expansion of pancreas stem cells

Hypoglycemia Preceding Fatal Car Collisions

Mixing Lantus with fast analogs has no effect on control

February 2006

Type 1 Diabetes Tied to Thinner Bones.  Study: Women With Type 1 Diabetes May Need Early Bone Density Test

January 2006

Low Blood Sugar and Memory

New generation of insulin pump - Starbridge secures global diabetes contract

December 2005

Getting a diabetic pancreas to regrow its islets

In New Zealand Pig cell diabetes treatment debated

New generation of insulin pump - Starbridge secures global diabetes contract

November 2005 

Diabetes findings pinpoint those at greater risk

October 2005

SA study finds diabetics' natural defence

July 2005

Tiny pump could transform lives

Joslin-Chaired Study Shows New Compound May Reduce Risk Of Vision Loss In Patients With Diabetes   New study shows that 32 milligrams per day of ruboxistaurin (RBX) may reduce the risk of moderate vision loss, especially in patients with diabetic macular edema.

May 2005

Hyperglycemia Slows Mental Functions.

The effects of glucose fluctuation on cognitive function and QOL: the functional costs of hypoglycaemia and hyperglycaemia among adults with type 1 or type 2 diabetes.Cox D, Gonder-Frederick L, McCall A, Kovatchev B, Clarke W.University of Virginia, Charlottesville, USA. Publication Types: * Review * Review, Tutorial PMID: 12166601 [PubMed - indexed for MEDLINE] J Pediatr Endocrinol Metab. 1996 Jul-Aug;9(4):455-61.

Acute hyperglycaemia impairs cognitive function in children with IDDM.

Conventional versus intensive diabetes therapy in children with type 1 diabetes: effects on memory and motor speed

Effect of acute hypoglycemia on visual information processing in adults with type 1 diabetes mellitus.

Neurocognitive functioning in children with type-1 diabetes with and without episodes of severe hypoglycaemia  Dev Med Child Neurol. 2003 Apr;45(4):262-8.

Severe hypoglycemia and long-term spatial memory in children with type 1 diabetes mellitus: a retrospective study

Hypoglycemia in children with type 1 diabetes: current issues and controversies

Nocturnal hypoglycemia detected with the Continuous Glucose Monitoring System in pediatric patients with type 1 diabetes J Pediatr. 2002 Nov;141(5):625-30

Decreased consciousness of hypoglycaemia and the incidence of severe hypoglycaemia in children and adolescents with diabetes type 1

The Impact of Severe Hypoglycemia and Impaired Awareness of Hypoglycemia on Relatives of Patients With Type 1 Diabetes

The best defense against hypoglycemia is to recognize it: is caffeine useful? Watson J, Kerr D. Bournemouth Diabetes and Endocrine Centre, Royal Bournemouth Hospital, Castle Lane East, Bournemouth BH7 7DW, United Kingdom.  Caffeine may increase an individual's sensitivity to hypoglycemia through the combined effects of reducing substrate delivery to the brain via constriction of the cerebral arteries, whilst simultaneously increasing brain glucose metabolism and augmenting catecholamine production

Hyperglycemia Slows Mental Functions in People with Diabetes

Quality of life in school-aged children with type 1 diabetes on intensive treatment and their parents Whittemore R, Urban AD, Tamborlane WV, Grey M

April 2005

Human blood cells coaxed to produce insulin  

March 2005

Single-Donor, Marginal-Dose Islet Transplantation in Patients With Type 1 Diabetes 

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